developmentally-regulated GTP-binding protein 2; DRG-2 (DRG2)

Function

• may play a role in cell proliferation, differentiation & cell death
• polyubiquitinated
  • induces proteolytic degradation
  • impaired by interaction with RWDD1 (putative)
• interacts with RWDD1 (putative)

Structure

belongs to the GTP1/OBG family

Compartment

cytoplasm

Expression

• expressed at highest levels in skeletal muscle, heart & kidney
• expressed at low levels in colon, thymus, spleen, small intestine, lung & leukocytes

More general terms

• guanine nucleotide regulatory protein (GNRP)
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1819
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1819
• OMIM: https://mirror.omim.org/entry/602986
• UniProt: http://www.uniprot.org/uniprot/P55039.html