IQ calmodulin-binding motif-containing protein 1 (nephrocystin-5, IQCB1, KIAA0036, NPHP5, OK/SW-cl85)

Function

• interacts with calmodulin

Structure

contains 4 IQ domains

Compartment

• localized to the outer segments & connecting cilia of photoreceptor cells

Alternative splicing

named isoforms=3

Expression

• ubiquitously expressed in fetal & adult tissues

Pathology

• defects in IQCB1 are the cause of Senior-Loken syndrome 5

More general terms

• calmodulin binding protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q15051.html