casein kinase 2-beta chain (phosvitin, CSNK2B ,CK2N, G5A)
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Function
- not catalytically active by itself
- stimulates the activity of the alpha & alpha' subunits 5-10 fold[1]
- stabilizes the alpha & alpha' subunits & alters their interactions with substrates & inhibitors
- phosphorylated by alpha subunit
Structure
- belongs to the casein kinase 2 subunit beta family
More general terms
Component of
References
- ↑ Jump up to: 1.0 1.1 Luscher B, Christenson E, Litchfield DW, Krebs EG, Eisenman RN. Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation. Nature. 1990 Apr 5;344(6266):517-22. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2157164
- ↑ Allende JE, Allende CC. Protein kinases. 4. Protein kinase CK2: an enzyme with multiple substrates and a puzzling regulation. FASEB J. 1995 Mar;9(5):313-23. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7896000