apoptosome complex

Function

• multimeric scaffold/procaspase complex.
• the "initiation complex" of apoptosis
• ssembly is regulated by bcl-2 family of proteins.

Structure

• consists of at least
  • APAF1
  • caspase-9 (proenzyme)
  • UACA

More general terms

• macromolecular complex

Additional terms

• apoptosis