C-type lectin domain family 10 member A; C-type lectin superfamily member 14; macrophage lectin 2; CD301 (CLEC10A, CLECSF13, CLECSF14, HML)

Function

• probable role in regulating adaptive immune response & innate immune response
• binds to terminal galactose & N-acetylgalactosamine units, linked to Ser or Thr (Ca+2-dependent)
• these sugar moieties are known as Tn-Ag & are expressed in a variety of carcinoma cells

Structure

• contains 1 C-type lectin domain

Compartment

• membrane; single-pass type 2 membrane protein (probable)

Alternative splicing

named isoforms=3

More general terms

• CD antigen
• C-type lectin superfamily

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10462
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:10462
• OMIM: https://mirror.omim.org/entry/605999
• UniProt: http://www.uniprot.org/uniprot/Q8IUN9.html