beta-arrestin-1; arrestin beta-1 (ARRB1 ARR1)

Function

• regulates beta-adrenergic receptor function
• beta-arrestins seem to bind phosphorylated beta-adrenergic receptors, thereby causing a significant impairment of their capacity to activate Gs proteins

Structure

belongs to the arrestin family

Alternative splicing

named isoforms=2

More general terms

• beta-arrestin

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=408
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:408
• OMIM: https://mirror.omim.org/entry/107940
• UniProt: http://www.uniprot.org/uniprot/P49407.html