calpastatin

Function

• cleaves & inactivates caspases, calpains
• role in postmortem tenderization of meat
• putative role in muscle protein degradation in living tissue
• phosphorylated

Structure

• 4 inhibitory domains
• N-terminus is blocked
• belongs to the protease inhibitor I27 (calpastatin) family

Alternative splicing

named isoforms=4

More general terms

• cysteine protease inhibitor
• PEST protein
• oligomerizing protein

Database

• UniProt: http://www.uniprot.org/uniprot/P20810.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:831
• OMIM: https://mirror.omim.org/entry/114090
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=831