cutaneous T-cell lymphoma-associated antigen 1; protein cTAGE-1; cancer/testis antigen 21.1; CT21.1 (CTAGE1)

Introduction

Cancer-testis antigen

Compartment

• membrane; multi-pass membrane protein

Alternative splicing

named isoforms=2

Expression

expressed in testes

Pathology

• expressed in cutaneous T-cell lymphoma (35%)
  • mycosis fungoides
  • Sezary syndrome
• expressed in head-neck cancer
• expressed in ovarian cancer

More general terms

• cutaneous T-cell lymphoma-associated antigen (cTAGE family)
• membrane protein
• testis-specific protein

Database

• OMIM: https://mirror.omim.org/entry/608856
• UniProt: http://www.uniprot.org/uniprot/Q9HC47.html
• UniProt: http://www.uniprot.org/uniprot/Q96RT6.html