selenocysteine-specific elongation factor; elongation factor sec; eukaryotic elongation factor, selenocysteine-tRNA-specific (EEFSEC, SELB)

Function

• translation factor necessary for incorporation of selenocysteine into proteins
• probably replaces EF-Tu for insertion of selenocysteine directed by the UGA codon
• selB binds GTP & GDP

Structure

• belongs to the GTP-binding elongation factor family selB subfamily

Compartment

• cytoplasm (putative)
• nucleus (potential)

More general terms

• translation elongation factor
• selenoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=60678
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:60678
• OMIM: https://mirror.omim.org/entry/607695
• UniProt: http://www.uniprot.org/uniprot/P57772.html