eukaryotic translation initiation factor 5A-2; eIF-5A-2; eIF-5A2; eukaryotic initiation factor 5A isoform 2 (EIF5A2)

Function

• precise role of eIF-5A in protein biosynthesis is not known
• promoting the formation of 1st peptide bond

Structure

• belongs to the eIF-5A family
• eIF-5A proteins only eukaryotic protein to have an hypusine residue

Expression

• highly expressed in testis

Pathology

• expressed in ovarian and colorectal cancer cell lines
• overexpressed in some cancer cells

More general terms

• initiation factor

Database

• OMIM: https://mirror.omim.org/entry/605782
• UniProt: http://www.uniprot.org/uniprot/Q9GZV4.html