NADH-cytochrome b5 reductase FLJ00377 (CYB5RL)

Function

• NADH-cytochrome b5 reductases are involved in desaturation & elongation of fatty acids, cholesterol
• biosynthesis, drug metabolism, &, in erythrocyte, methemoglobin reduction (putative)

NADH + 2 ferricytochrome b5 <--> NAD+ + H+ + 2 ferrocytochrome b5

Cofactor: FAD (putative)

Structure

• belongs to the flavoprotein pyridine nucleotide cytochrome reductase family

Alternative splicing

named isoforms=3

More general terms

• oxidoreductase
• flavoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q6IPT4.html