electron transfer flavoprotein-beta subunit (ETFB)

Function

• subunit of electron transfer flavoprotein

Cofactor:

• binds 1 FAD per dimer
• binds 1 AMP per subunit

Structure

• belongs to the ETF beta-subunit/fixA family

Compartment

mitochondrial matrix

Alternative splicing

named isoforms=2

Expression

• abundant in liver, heart & skeletal muscle
• weak expression is seen in the brain, placenta, lung, kidney & pancreas

Pathology

• defects in ETFA associated with glutaric aciduria-2

More general terms

• protein subunit
• flavoprotein

Component of

• electron transfer flavoprotein (ETF)

Database

• OMIM: https://mirror.omim.org/entry/130410
• OMIM: https://mirror.omim.org/entry/231680
• UniProt: http://www.uniprot.org/uniprot/P38117.html