peroxisomal trans-2-enoyl-CoA reductase (TERP; HPDHase; pVI-ARL; 2,4-dienoyl-CoA reductase-related protein; DCR-RP; PECR)

Function

• fatty acid biosynthesis pathway
• role in chain elongation of fatty acids
• has no 2,4-dienoyl-CoA reductase activity
• interacts with PEX5, probably required to target it into peroxisomes

acyl-CoA + NADP+ <--> trans-2,3-dehydroacyl-CoA + NADPH

Structure

• belongs to the short-chain dehydrogenases/reductases (SDR) family

Compartment

peroxisome

Alternative splicing

named isoforms=2

More general terms

• enzyme

Database

• OMIM: https://mirror.omim.org/entry/605843
• UniProt: http://www.uniprot.org/uniprot/Q9BY49.html