cytosolic purine 5'-nucleotidase (5'-nucleotidase cytosolic 2, NT5C2, NT5B, NT5CP, PNT5)

Function

• role in the maintenance of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases
• preferentially hydrolyzes inosine 5-prime-monophosphate (IMP) & other purine nucleotides
• allosterically activated by ATP

5'-ribonucleotide + H2O <--> ribonucleoside + phosphate

Compartment

cytoplasm

Pathology

• defects or misregulation may be related to the urate production in hyperuricemia & gout

More general terms

• enzyme

Database

• OMIM: https://mirror.omim.org/entry/600417
• UniProt: http://www.uniprot.org/uniprot/P49902.html