eukaryotic translation initiation factor 3 subunit L; eIF3l; eukaryotic translation initiation factor 3 subunit 6-interacting protein; eukaryotic translation initiation factor 3 subunit E-interacting protein (EIF3L, EIF3EIP, EIF3S6IP, HSPC021, HSPC025, MSTP005)

Function

• component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis
• EIF3L is a labile subunit that binds to the eIF-3 complex via EIF3B
• interacts with RRN3 (putative)

Structure

belongs to the eIF-3 subunit L family

Compartment

cytoplasm (probable)

More general terms

• protein subunit

Additional terms

• eukaryotic initiation factor 3 subunit 6 (eukaryotic translation initiation factor 3 subunit E, eiF3 p48, mammary tumor-associated protein INT-6, viral integration site protein INT-6, eIF3e, EIF3S6)

Component of

• eukaryotic initiation factor 3; ribosome dissociation factor (eIF3)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=51386
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:51386
• UniProt: http://www.uniprot.org/uniprot/Q9Y262.html