prolow-density lipoprotein receptor-related protein 1 (LRP1 precursor)

Function

• cleaved into a 85 kD membrane-spanning subunit (LRP1-beta) & a 515 kD large extracellular domain (LRP1-alpha) that remains non-covalently associated
• see LRP1

Structure

• belongs to the LDLR family
• contains 22 EGF-like domains
• contains 31 LDL-receptor class A domains
• contains 34 LDL-receptor class B repeats

More general terms

• phosphoprotein
• Ca+2 binding protein
• glycoprotein
• protein precursor

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4035
• OMIM: https://mirror.omim.org/entry/107770
• UniProt: http://www.uniprot.org/uniprot/Q07954.html