CAP-Gly domain-containing linker protein 2; cytoplasmic linker protein 115; CLIP-115; cytoplasmic linker protein 2; Williams-Beuren syndrome chromosomal region 3 protein; Williams-Beuren syndrome chromosomal region 4 protein (CLIP2, CYLN2, KIAA0291, WBSCR3, WBSCR4, WSCR4)

Function

• links microtubules to dendritic lamellar body (putative)
• control of brain-specific organelle translocations (putative)
• interacts with CLASP1 & CLASP2

Structure

contains 2 CAP-Gly domains

Compartment

cytoplasm, associated with cytoskeleton

Alternative splicing

named isoforms=2

Pathology

• haploinsufficiency associated with Williams-Beuren syndrome

More general terms

• cytoskeletal protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7461
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7461
• OMIM: https://mirror.omim.org/entry/603432
• UniProt: http://www.uniprot.org/uniprot/Q9UDT6.html