HRAS-like suppressor 3; H-rev 107 protein homolog; HREV107-3; renal carcinoma antigen NY-REN-65 (HRASLS3, HREV107, PLA2G16)

Function

• tumor suppressor
• role in interferon-dependent cell death

Structure

• belongs to the H-rev107 family

Expression

• ubiquitously expressed, except in haematopoetic cells
• found in normal ovarian epithelial cells

Pathology

• consistently down-regulated in tumorigenic human cell lines
• down-regulated in ovarian carcinomas

More general terms

• H-rev107 family
• anti-oncoprotein (tumor suppressor protein)
• membrane protein

Database

• UniProt: http://www.uniprot.org/uniprot/P53816.html