exostosin-like 3; glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; tumor suppressor protein EXTL3; multiple exostosis-like protein 3; Hereditary multiple exostoses gene isolog; EXT-related protein 1 (EXTL3, EXTL1L, EXTR1, KIAA0519)

Function

• probable glycosyltransferase
• glycan metabolism; heparan sulfate biosynthesis

Structure

• belongs to the glycosyltransferase 47 family

Compartment

• endoplasmic reticulum membrane
• single-pass type 2 membrane protein

Expression

ubiquitous

Notes

uncertain whether Met-1, Met-6 or Met-20 is the initiator

More general terms

• glycosyltransferase
• membrane protein
• anti-oncoprotein (tumor suppressor protein)
• glycoprotein

Additional terms

• exostosin

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2137
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2137
• OMIM: https://mirror.omim.org/entry/605744
• UniProt: http://www.uniprot.org/uniprot/O43909.html