NHP2-like protein 1 (high mobility group-like nuclear protein 2 homolog 1, U4/U6.U5 tri-snRNP 15.5 kD protein, OTK27, hSNU13, sperm-specific antigen 1, SSFA1, NHP2L1)

Function

• binds to the 5' stem-loop of U4 snRNA
• role in the late stage of spliceosome assembly (putative)
• conformational change upon RNA-binding
• interacts with RAD17

Compartment

• nucleus, nucleolus
• concentrated in dense fibrillar component of nucleolus

Expression

ubiquitous

More general terms

• RNA-binding protein
• nuclear protein

Database

• OMIM: https://mirror.omim.org/entry/601304
• OMIM: https://mirror.omim.org/entry/601876
• UniProt: http://www.uniprot.org/uniprot/P55769.html