cleavage & polyadenylation specificity factor 5 (cleavage & polyadenylation specificity factor 25 kD subunit, CPSF 25 kD subunit, pre-mRNA cleavage factor Im 25-kD subunit, nucleoside diphosphate-linked moiety X motif 21, Nudix motif 21, NUDT21, CFIM25, CPSF25, CPSF5)

Function

• component of the cleavage factor Im (CFIm)
• binds to cleavage & polyadenylation RNA substrates
• interacts with CPSF6, PAPOLA, PABPN1, SNRP70

Compartment

• nucleus
• in punctate subnuclear structures, localized adjacent to nuclear speckles (paraspeckles)

More general terms

• protein subunit
• nuclear protein
• RNA-binding protein
• phosphoprotein
• nucleoside diphosphate-linked moiety X motif

Component of

• pre-mRNA cleavage factor Im complex

Database

• OMIM: https://mirror.omim.org/entry/604978
• UniProt: http://www.uniprot.org/uniprot/O43809.html