Ras GTPase-activating protein-binding protein 2; G3BP-2; GAP SH3 domain-binding protein 2 (G3BP2, KIAA0660)

Function

• probable scaffold protein
• may be involved in mRNA transport
• Arg-457 & Arg-468 are dimethylated, probably to asymmetric dimethylarginine
• binds to the N-terminal domain of I-kappa-B-alpha

Structure

• contains 1 NTF2 domain
• contains 1 RRM domain (RNA recognition motif)

Compartment

cytoplasm

Alternative splicing

named isoforms=2; A, B

More general terms

• RNA-binding protein
• SH3 domain-binding protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9908
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9908
• UniProt: http://www.uniprot.org/uniprot/Q9UN86.html