nuclear transport factor 2; NTF-2; placental protein 15; PP15 (NUTF2, NTF2)

Function

• facilitates protein transport into the nucleus
• interacts with the nucleoporin p62 & with Ran
• acts at a relatively late stage of nuclear protein import, subsequent to the initial docking of nuclear import ligand at the nuclear envelope
• could be part of a multicomponent system of cytosolic factors that assemble at the nuclear pore complex during nuclear import

Structure

• homodimer
• contains 1 NTF2 domain

Compartment

cytoplasm

More general terms

• secreted protein
• placental protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10204
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:10204
• OMIM: https://mirror.omim.org/entry/605813
• UniProt: http://www.uniprot.org/uniprot/P61970.html