heterogeneous nuclear ribonucleoprotein R; hnRNP R (HNRNPR, HNRPR)

Function

• component of ribonucleosomes
• like other hnRNPs, plays role in processing of precursor mRNA in the nucleus
• identified in the spliceosome C complex

Structure

contains 3 RRM domains (RNA recognition motifs)

Compartment

• nucleus, nucleoplasm, cytoplasm
• localized in cytoplasmic mRNP granules containing untranslated mRNAs

Alternative splicing

named isoforms=2

More general terms

• heterogeneous nuclear ribonucleoprotein (hnRNP)
• RNA-binding protein

Component of

• spliceosome C complex

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10236
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:10236
• OMIM: https://mirror.omim.org/entry/607201
• UniProt: http://www.uniprot.org/uniprot/O43390.html