heterogeneous nuclear ribonucleoprotein H2; hnRNP H2; FTP-3; heterogeneous nuclear ribonucleoprotein H'; hnRNP H' (HNRNPH2, FTP3, HNRPH2)

Function

• component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm
• binds poly(rG)
• interacts with TXNL4/DIM1

Structure

• contains 3 RRM domains (RNA recognition motifs)

Compartment

nucleus, nucleoplasm

Expression

expressed ubiquitously

More general terms

• heterogeneous nuclear ribonucleoprotein (hnRNP)
• RNA-binding protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3188
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3188
• OMIM: https://mirror.omim.org/entry/300610
• UniProt: http://www.uniprot.org/uniprot/P55795.html