dual specificity protein phosphatase 11 (RNA/RNP complex-intereracting phosphatase, phosphatase that interacts with RNA/RNP complex 1, DUSP11, PIR1)

Function

• possesses RNA 5'-triphosphatase & diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity
• binds to RNA
• may participate in nuclear mRNA metabolism
• interacts with SFRS7 & SFRS9/SRP30C

Structure

• belongs to the protein-tyrosine phosphatase family non-receptor class dual specificity subfamily
• contains 1 tyrosine-protein phosphatase domain

Compartment

nucleus

Alternative splicing

named isoforms=2

More general terms

• dual specificity phosphatase
• RNA-binding protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8446
• OMIM: https://mirror.omim.org/entry/603092
• UniProt: http://www.uniprot.org/uniprot/O75319.html