Seizure 6-like protein 2 (SEZ6L2 PSK UNQ1903/PRO4349)

Function

• may contribuates to specialized endoplasmic reticulum functions in neurons

Structure

• belongs to the SEZ6 family
• contains 3 CUB domains
• contains 5 Sushi (CCP/SCR) domains

Compartment

• cell membrane, endoplasmic reticulum membrane

Alternative splicing

named isoforms=4

Pathology

• detected on cell surface in lung-cancers
• increased expression in the majority of primary lung cancers & lung-cell lines tested
• may serve as a prognostic marker for lung cancers

More general terms

• glycoprotein
• membrane protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q6UXD5.html