solute carrier family 26 member 9 (anion transporter/exchanger protein 9, SLC26A9)
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Function
- DIDS- & thiosulfate-sensitive anion exchanger mediating chloride, sulfate & oxalate transport
- mediates chloride/bicarbonate exchange or chloride- independent bicarbonate extrusion thus assuring bicarbonate secretion
- inhibited by ammonium & thiosulfate
Structure
- belongs to the SLC26A/sulP transporter family
- contains 1 STAS domain
Compartment
membrane
Expression
- predominantly expressed in lung at the luminal side of the bronchiolar & alveolar epithelium of lung.
- to a lower extent, also espressed in pancreas & prostate