sphingolipid delta(4)-desaturase DES1 (degenerative spermatocyte homolog 1, membrane lipid desaturase, migration-inducing gene 15 protein, DEGS1, DES1, MLD, MIG15)

Function

• has sphingolipid-delta-4-desaturase activity
• converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine)

Structure

• belongs to the fatty acid desaturase family, DEGS subfamily

Compartment

endoplasmic reticulum membrane

Expression

ubiquitous

More general terms

• oxidoreductase
• membrane protein

Database

• UniProt: http://www.uniprot.org/uniprot/O15121.html