armadillo repeat-containing protein 10 (splicing variant involved in hepatocarcinogenesis protein, ARMC10, SVH, PSEC0198)

Function

• role in cell survival & cell growth (putative)

Structure

contains 1 ARM repeat

Compartment

endoplasmic reticulum membrane

Alternative splicing

named isoforms=4

Expression

• expressed in all tissues tested
• higher expression in placenta, liver, kidney, heart & brain

Pathology

• depletion of isoform 2 results in cell apoptosis
• overexpression of isoform 2 leads to accelerated growth rate & tumorogenicity

More general terms

• armadillo repeat-containing X-linked protein
• glycoprotein
• membrane protein
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8N2F6.html