adipocyte-specific adhesion molecule (Coxsackie- & adenovirus receptor-like membrane protein, CAR-like membrane protein, ASAM, ACAM, CLMP, UNQ318/PRO363)

Function

• may be involved in the cell-cell adhesion
• may play a role in adipocyte differentiation & development of obesity

Structure

• contains 2 Ig-like C2-type domain (immunoglobulin-like)

Compartment

cell junction, tight junction

Expression

• predominantly expressed in epithelial cells within different tissues & in white adipose tissue
• expressed in small intestine & placenta > heart, skeletal muscle, colon, spleen, kidney & lung > liver & peripheral blood leukocytes
• up-regulated in mature adipocytes & adipocyte tissue of obese individuals

More general terms

• glycoprotein
• membrane protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9H6B4.html