protein KIAA1324 (estrogen-induced gene 121 protein, KIAA1324, EIG121, UNQ2426/PRO4985)

Function

• marker of hyperestrogenic state and estrogen-related type 1 endometrial carcinoma

Compartment

membrane

Alternative splicing

named isoforms=4

Expression

• expressed in normal endometrium but
• induced by estrogen replacement therapy

Pathology

• marker of estrogen-related type 1 endometrial carcinoma
• overexpressed in endometroid tumors

More general terms

• glycoprotein
• membrane protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q6UXG2.html