elongation of very long chain fatty acids protein 1 (ELOVL1, SSC1, CGI-88)

Function

• role in tissue-specific synthesis of very long chain fatty acids & sphingolipids
• may catalyze one or both of the reduction reactions in fatty acid elongation, i.e., conversion of beta-ketoacyl CoA to beta-hydroxyacyl CoA or reduction of trans-2-enoyl CoA to the saturated acyl CoA derivative

Structure

• di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins
• belongs to the ELO family

Compartment

edoplasmic reticulum membrane

More general terms

• oxidoreductase
• membrane protein
• elongation of very long chain fatty acids protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9BW60.html