RING finger protein 43 (RNF43)

Structure

contains 1 RING-type zinc finger

Compartment

membrane, secreted

Expression

expressed in fetal kidney, fetal lung

Pathology

• expressed in hepatocellular carcinomas, lung adenocarcinomas
• overexpressed in colorectal cancer cell lines
• acts as a cytotoxic T lymphocyte tumor antigen may be used as a target for cancer immunotherapy

More general terms

• ring finger protein
• membrane protein
• secreted protein
• glycoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q68DV7.html