Golgi phosphoprotein 4; Golgi integral membrane protein cis; GIMPc; Golgi-localized phosphoprotein of 130 kD; Golgi phosphoprotein of 130 kD (GOLPH4, GIMPC, GPP130, GOLIM4)
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Function
- plays a role in endosome to Golgi protein trafficking
- mediates protein transport along the late endosome-bypass pathway from the early endosome to the Golgi
- phosphorylated by c-AMP-dependent kinases in its lumenal part (putative)
Structure
- O-glycosylated, modified by sialic acid residues
- N-glycosylated, N-glycans are probably of the complex type & modified by sialic acid residues
- belongs to the GOLPH4 family
Compartment
- Golgi membrane, endosome membrane
- localizes to cis & medial Golgi cisternae
- probably cycles between early Golgi & endosome