leucine-rich repeat-containing protein 1 (LAP & no PDZ protein, LANO adapter protein, LRRC1, LANO)

Function

• interacts with DLG1 & DLG4
• may form a complex with DLG1 & ERBB2IP
• interaction between LRRC1 & ERBB2IP is indirect

Structure

• contains 17 LRR repeats (leucine-rich repeats)

Compartment

• cytoplasm, peripheral membrane
• localized at the basolateral side of epithelial cells

Alternative splicing

named isoforms=2

Expression

• expressed in testis & placenta > heart, lung, kidney, thyroid, trachea, colon, prostate, pancreas

More general terms

• membrane protein
• leucine-rich repeat-containing protein (LRRC)

Database

• OMIM: https://mirror.omim.org/entry/608195
• UniProt: http://www.uniprot.org/uniprot/Q9BTT6.html