protein APCDD1; adenomatosis polyposis coli down-regulated 1 protein (APCDD1, DRAPC1, FP7019)

Function

• developmental target gene of the Wnt (Beta-catenin) pathway

Compartment

membrane

Expression

• expressed in heart, pancreas, prostate, ovary > lung, liver, kidney, spleen, thymus, colon, peripheral lymphocytes
• transcriptionally regulated by the CTNNB1/TF7L2 complex

Pathology

• role in colorectal carcinoma

More general terms

• membrane protein
• glycoprotein

Database

• OMIM: https://mirror.omim.org/entry/607479
• UniProt: http://www.uniprot.org/uniprot/Q8J025.html