transmembrane glycoprotein NMB (transmembrane glycoprotein HGFIN, GPNMB, HGFIN, NMB, UNQ1725/PRO9925)

Function

• may be a melanogenic enzyme

Structure

• contains 1 PKD domain

Compartment

membrane

Alternative splicing

named isoforms=2

Expression

not restricted to the melanocytic lineage

Pathology

• expression in poorly metastatic melanoma cell lines
• no expression in highly metastatic melanoma cell lines

More general terms

• membrane protein
• glycoprotein

Database

• OMIM: https://mirror.omim.org/entry/604368
• UniProt: http://www.uniprot.org/uniprot/Q14956.html