BMP & activin membrane-bound inhibitor homolog (transmembrane protein NMA, non-metastatic gene A protein, BAMBI, NMA)

Function

• negatively regulates TGF-beta signaling

Compartment

membrane

Expression

• expressed in renal medulla, placenta, spleen > renal cortex, liver, prostate, gut
• Not expressed in normal skin
• expression is high in melanocytes

Pathology

• diminished or no expression in metastatic melanoma

More general terms

• membrane protein
• glycoprotein

Database

• OMIM: https://mirror.omim.org/entry/604444
• UniProt: http://www.uniprot.org/uniprot/Q13145.html