IgG receptor FcRn large subunit p51 (FcRn, neonatal Fc receptor, IgG Fc fragment receptor transporter alpha chain, FCGRT, FCRN)

Function

• binds to the Fc region of monomeric immunoglobulin gamma
• mediates the uptake of IgG from milk
• role in transfer of immunoglobulin G from mother to fetus (putative)
• forms an MHC class 1-like heterodimer with beta-2 microglobulin

Structure

• belongs to the immunoglobulin superfamily

Compartment

membrane

More general terms

• protein subunit
• membrane protein
• immunoglobulin superfamily protein

Database

• OMIM: https://mirror.omim.org/entry/601437
• UniProt: http://www.uniprot.org/uniprot/P55899.html