sialylation

Introduction

Transfer N-acetylneuraminic acid to sialoglycoproteins

Function:

• cell adhesion
• signal transduction
• tumorigenicity & metastatic behavior of malignant cells

Pathology

• defects associated with sialuria

More general terms

• enzymatic reaction

Additional terms

• N-acylneuraminate cytidylyltransferase (CMP-N-acetylneuraminic acid synthetase, CMP-NeuNAc synthetase, CMAS)
• sialic acid; N-acetyl neuraminic acid (NANA)
• sialoglycoprotein
• sialuria; sialic acid storage disorder; N-acetylneuraminic acid storage disease; Salla disease