neural proliferation differentiation & control protein 1; NPDC-1 (NPDC1)

Function

• suppresses oncogenic transformation in neurons & non-neural cells & down-regulates neural cell proliferation
• may be involved in transcriptional regulation (putative)

Structure

belongs to the NPDC1/cab-1 family

Compartment

membrane (potential)

Expression

• strongly expressed in adult brain; especially in hippocampus, frontal lobe & temporal lobe

More general terms

• phosphoprotein
• membrane protein

Additional terms

• Sjogren's syndrome (autoimmune epitheliitis)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=56654
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:56654
• OMIM: https://mirror.omim.org/entry/605798
• UniProt: http://www.uniprot.org/uniprot/Q9NQX5.html