thioredoxin domain-containing protein 1; thioredoxin-related transmembrane protein 1; transmembrane Trx-related protein (TMX1 TMX, TXNDC, TXNDC1, PSEC0085 UNQ235/PRO268)

Function

• may participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide & catalyze dithiol-disulfide exchange reactions

Structure

contains 1 thioredoxin domain

Compartment

• membrane; single-pass type 1 membrane protein (putative)
• endoplasmic reticulum membrane
• predominantly found in the endoplasmic reticulum

Expression

• ubiquitous
• highly expressed in kidney, liver, placenta & lung

More general terms

• thioredoxin domain-containing protein
• membrane protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=81542
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:81542
• OMIM: https://mirror.omim.org/entry/610527
• UniProt: http://www.uniprot.org/uniprot/Q9H3N1.html