CUB & SUSHI domain-containing protein 3; CUB & SUSHI multiple domains protein 3 (CSMD3, KIAA1894)

Structure

• belongs to the CSMD family
• contains 14 CUB domains
• contains 28 Sushi (CCP/SCR) domains

Compartment

• cell membrane; multi-pass membrane protein

Alternative splicing

named isoforms=5

Expression

• weakly expressed in most tissues, except in brain
• expressed at intermediate level in brain, including cerebellum, substantia nigra, thalamus, spinal cord, hippocampus & fetal brain. also expressed in testis

More general terms

• membrane protein
• human longevity protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=114788
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:114788
• OMIM: https://mirror.omim.org/entry/608399
• UniProt: http://www.uniprot.org/uniprot/Q7Z407.html