zinc finger protein 261; zinc finger MYM-type protein 3 (ZMYM3, DXS6673E, KIAA0385, ZNF261)

Function

• role in the regulation of cell morphology & cytoskeletal organization
• may be a component of a BHC histone deacetylase complex

Structure

• contains 9 MYM-type Zn+2 fingers

Compartment

nucleus (putative)

Alternative splicing

named isoforms=2

Expression

• expressed inn brain > muscle, heart > other tissues
• not epressed in placenta

Pathology

• chromosomal translocation t(X;13)(q13.1;?) involving ZMYM3 may be a cause of X-linked mental retardation

More general terms

• nuclear protein
• zinc finger protein
• phosphoprotein

Component of

• BHC histone deacetylase complex

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9203
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9203
• OMIM: https://mirror.omim.org/entry/300061
• UniProt: http://www.uniprot.org/uniprot/Q14202.html