proteolipid protein 2; intestinal membrane A4 protein; differentiation-dependent protein A4 (PLP2, A4)

Function

• may play a role in cell differentiation in the intestinal epithelium

Structure

contains 1 MARVEL domain

Compartment

membrane

Expression

• enriched in colonic mucosa
• expression of A4 follows a gradient along the crypto-villus axis with the most abundant message occurring in the lower half of the crypt

More general terms

• membrane protein
• glycoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5355
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5355
• OMIM: https://mirror.omim.org/entry/300112
• UniProt: http://www.uniprot.org/uniprot/Q04941.html