vesicular glutamate transporter 3 (VGluT3, solute carrier family 17 member 8, SLC17A8, VGLUT3)

Function

• mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells
• may also mediate the transport of inorganic phosphate

Structure

• belongs to the major facilitator superfamily Na+/anion cotransporter family, VGLUT subfamily

Compartment

• cytoplasmic vesicle, secretory vesicle,
• synaptic vesicle membrane (putative)

Alternative splicing

named isoforms=2

Expression

• expressed in amygdala, cerebellum, hippocampus, medulla, spinal cord & thalamus

More general terms

• transmembrane 12 protein
• glycoprotein
• solute carrier family 17 (SLC17, SLC17A)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2462
• OMIM: https://mirror.omim.org/entry/607557
• UniProt: http://www.uniprot.org/uniprot/Q8NDX2.html