serine incorporator 5 (SERINC5, C5orf12)

Function

• enhances the incorporation of serine into phosphatidylserine & sphingolipids
• may play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes (putative)

Structure

belongs to the TDE1 family

Compartment

endoplasmic reticulum

Alternative splicing

named isoforms=3

Expression

• expressed in placenta, skeletal muscle, spleen, thymus, testis & peripheral leukocyte > heart, liver & fetal brain

More general terms

• glycoprotein
• transmembrane 9 protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2569
• UniProt: http://www.uniprot.org/uniprot/Q86VE9.html