vesicular glutamate transporter 2 (VGluT2, solute carrier family 17 member 6, differentiation-associated Na+-dependent inorganic phosphate cotransporter, differentiation-associated BNPI, SLC17A6, DNPI, VGLUT2)

Function

• mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells
• may also mediate the transport of inorganic phosphate

Structure

• belongs to the major facilitator superfamily Na+/anion cotransporter family. VGLUT subfamily

Compartment

• cytoplasmic vesicle, secretory vesicle,
• synaptic vesicle membrane (putative)

Expression

• predominantly expressed in adult brain
• expressed in fetal brain

More general terms

• glycoprotein
• transmembrane 12 protein
• solute carrier family 17 (SLC17, SLC17A)
• major facilitator superfamily (MFS)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5708
• OMIM: https://mirror.omim.org/entry/607563
• UniProt: http://www.uniprot.org/uniprot/Q9P2U8.html