eosinophil cationic protein (ribonuclease 3, RNase3, ECP)

Function

• cytotoxin & helminth toxin
• antibacterial activity
• low-efficiency ribonuclease activity
• wide variety of biological activities

Structure

• belongs to the pancreatic ribonuclease family

Compartment

matrix of eosinophil's large specific granule

Pathology

• induces neurotoxic effect known as the Gordon phenomenon

Laboratory

• eosinophil cationic protein in nasal fluid
• eosinophil cationic protein in serum

More general terms

• endoribonuclease
• glycoprotein

Additional terms

• ribonuclease 3 (Drosha, p241, RNase3, RNASEN, RN3, RNASE3L)

Database

• UniProt: http://www.uniprot.org/uniprot/P12724.html
• OMIM: https://mirror.omim.org/entry/131398